List of Articles by MeSH

ANESTHESIA, DENTAL + adverse effects

NOTES:

*Articles are cited according to Uniform Requirements by International Committee of Medical Journal Editors - ICMJE and NLM Style Guide for Authors, Editors and Publishers

Žagar D, Gašparović S. Systemic Side-Effects of Local Anaestheics in Dental Medicine. Acta Stomatol Croat. 2004;38(4):286-7.

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Title in English:	Systemic Side-Effects of Local Anaestheics in Dental Medicine
Title in Croatian:	Sustavne nuspojave lokalnih anestetika u stomatologiji
Type of Article:	congress abstract
MeSH:	ANESTHESIA, DENTAL + adverse effects
Abstract:	Systematic side effects are the consequences of non-selective pharmacodynamic interactions of local anaesthetic with tissues and organs outside the oral cavity.The aim of the study was to give a short review of systematic side effects, their pathophysiology, clinical appearance and therapy, which the dentist should apply in the dental surgery until the arrival of urgent medical help.We classified systematic side-effects into: psychogenic reactions, toxic reactions, reactions to vasoconstrictors and reactions of hypersensitivity.The most frequent clinical presentation of psychogenic reaction is syncope, a consequence of vasovagal reactions or hyperventilation. The condition requires the cessation of the dental operation and placing the patient in Trendelenburg's position.Toxic reactions occur when the concentration of anaesthetic in the blood exceeds the minimal toxic concentration. They can occur in the case of overdosing and intravascular application of the anaesthetic. Toxicity can be interpreted in the central nervous and cardiovascular system. Involvement of the cardiovascular system can be seen in AV block of different degrees or asystolia, which requires resuscitation.Toxic reactions in CNS are interpreted as excitation or depression. The most serious presentations of excitation are clonic-tonic cramps, which are halted by intravenous application of diazepam. Respiratory depression requires mechanical ventilation of the patient.Reaction to vasoconstrictors is the result of the stimulation of adrenergic receptors in the cardiovascular system, and symptoms are transient raised frequency of cardiac and blood pressure, and also arrhythmia. In the case of mild symptoms the patient should be sedated and kept under observation, and in the case of significantly raised blood pressure medication therapy applied.Reactions of hypersensitivity may be local or systematic. Local reactions involve changes on the skin and mucous membrane such as erythema and urticaria, and they require intramuscular application of an antihistaminic. Systematic hypersensitivity includes laryngo broncho spasm with a fall in blood pressure. The therapy choice is intravenous application of adrenaline, antihistaminic and corticosteroids and ventilation of the patient with 100% oxygen.Algorithm of clinical procedure is proposed for easier differential diagnosis and therapy.

Sandev S, Knežević G. Comparative Analysis of Possible Complications During Oralsurgical Operations Under General Endotracheal and Short Inhalation Anaesthesia. Acta Stomatol Croat. 2004;38(4):285-6.

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Title in English:	Comparative Analysis of Possible Complications During Oralsurgical Operations Under General Endotracheal and Short Inhalation Anaesthesia
Title in Croatian:	Usporedba raščlamba mogućih komplikacija tijekom oralnokirurških zahvata u općoj endotrahealnoj i kratkotrajnoj inhalacijskoj anesteziji
Type of Article:	congress abstract
MeSH:	ANESTHESIA, DENTAL + adverse effects ORAL SURGICAL PROCEDURES
Abstract:	The object of the study was to investigate the numerous possible complications during oralsurgical procedures in two groups of patients. The patients in the first group were treated under general brief inhalation anaesthesia, i.e. inhalation sedation, while the patients in the second group were treated under general inhalation anaesthesia with intubation. The results of monitoring the parameters of general physiological status and local complications during work were recorded in a previously prepared questionnaire. We determined greater frequency of raised blood pressure, rapid pulse, low oxygenation, fractured teeth during extraction, increased bleeding during and after the procedure, breathing difficulties due to blood and secretion in the respiratory tract, the presence of a foreign body in the respiratory tract, and bruising of the soft tissues of the oral cavity in the group of patients treated under inhalation sedation. Vomiting after the operation was frequently registered in the group of patients under general inhalation anaesthesia with intubation, which is a consequence of the longer duration and greater depth of anaesthesia. The results of the investigation, compared with the experience and investigations in the available literature, indicate the need for a more cautious approach to inhalation sedation and the need for further more comprehensive investigations in this field.The investigation showed that during brief inhalation anaesthesia general and local complications can be expected which may threaten the health of the patient.Every more serious complication during work with the application of short inhalation anaesthesia requires the cessation of work and plan for intubation of the patient in order for the operation to be concluded, e.g. fracture of the root which cannot be removed. There were no such examples in the examined sample, although data exists on the same in the Clinical Department of Oral Surgery.

Filipović I, Zaklan-Kavić D. [Convulsions - reaction to intoxication with Cystocain DS]. Acta Stomatol Croat. 1990;24(1):61-7.

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Zaklan-Kavić D. [Trismus after mandibular anesthesia]. Acta Stomatol Croat. 1982;16(4):311-4.

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