List of Articles by MeSH

ANTI-INFECTIVE AGENTS, LOCAL

1. Brugger W, Hofer V, Städtler P. Antibacterial Effects of Endodontic Dressings on Enterococcus Faecalis in Human Root Dentine. Acta Stomatol Croat. 2007;41(4):326-36.
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   Title in English:	Antibacterial Effects of Endodontic Dressings on Enterococcus Faecalis in Human Root Dentine
   Title in Croatian:	Antibakterijski učinak endodontskog uloška na Enterococcus faecalis u dentinu zubnog korijena
   Type of Article:	original scientific paper
   MeSH:	ENDODONTICS ENTEROCOCCUS FAECALIS DENTINE, SECONDARY ANTI-INFECTIVE AGENTS, LOCAL
   Abstract:	The aim of this in vitro study was to assess antimicrobial activity of calcium hydroxide (Calasept) and chlorhexidine (CHX) in various concentrations with respect to Enterococcus faecalis in human root dentine up to 100 μm. Material and Methods: Forty-eight human root canals were enlarged to standard size (ISO 40) and inoculated with Enterococcus faecalis for 21 days. After inoculation the canals were medicated with one of the following: 2 %, 1 % and 0.2 % chlorhexidin gel, Chlorhexidine releasing gutta-percha points (active point), calcium hydroxide and aqua distillate (aqua dest.). Aqua dest. served as control medium. At the end of a disinfection period of one week dentine samples were collected with reamer and H-file (ISO 45 and 50) and put onto Columbia agar plates. Results: Bacterial growth was assessed by counting the colony forming units (CFU) after 24 hours and 48 hours of incubation. CHX gels could penetrate dentine up to 100 μm. Two % CHX gel is slightly stronger than 1 % CHX gel (p-value 0.0925) only in the peripheral dentine sample after 48 hours of incubation, and 0.2 % CHX gel had less effects on E. faecalis than 2 % CHX (p-value 0.0191). In the central dentine sample no difference between the CHX gels could be observed. In general, CHX gels were more effective than the other medicaments tested. No significant difference between Ca(OH)2 and Aqua dest. could be observed. Conclusion: For effective elimination of E. faecalis, especially in deeper dentine-layers, CHX concentrations of at least 1 % are necessary. An intracanal, interappointment dressing of 2 % CHX may have the potential to eliminate E. faecalis in vivo.

2. Karlović Z, Anić I, Miletić I, Prpić-Mehičić G, Pezelj-Ribarić S, Maršan T. Antibacterial activity of halothane, eucalyptol and orange oil. Acta Stomatol Croat. 2000;34(3):303-9.
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   Title in English:	Antibacterial activity of halothane, eucalyptol and orange oil
   Title in Croatian:	Antibakterijsko djelovanje halotana, eukaliptola i narančina ulja
   Type of Article:	original scientific paper
   MeSH:	HALOTHANE MENTHOL OILS + pharmacology STAPHYLOCOCCUS AUREUS ENTEROCOCCUS FAECALIS FRUITS ANTI-INFECTIVE AGENTS, LOCAL
   Abstract:	Staphylococcus aureus and Enterococcus faecalis species were used for the experiment. 0,5 McFarland bacterial inoculum was diluted using saline in proportions 1:10, 1:10 2, 1:10 3, 1:10 4, 1:10 5 and 1:10 6. 0.2 millilitre of solving agent was mixed with an equal quantity of bacterial suspension. Sixty specimens, 10 for each proportion, were prepared. Specimens were hermetically closed and left for 10 and 30 minutes. 0.1 millilitre of each specimen was planted to the blood agar and put in the thermostat at 37°C for 24 hours. The procedure was repeated twice. Halothane exhibited greatest antibacterial activity, destroying all concentrations of Staphylococcus aureus and Enterococcus faecalis. Eucalyptol showed activity towards Staphylococcus aureus, while orange oil did not show any antibacterial effect on the examined bacteria.

3. Pezelj-Ribarić S, Brekalo I, Abram M, Miletić I, Anić I, Ferreri S, Foško-Glavaš L. Antibacterial effects of various root filling materials. Acta Stomatol Croat. 2000;34(1):51-7.
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   Title in English:	Antibacterial effects of various root filling materials
   Title in Croatian:	Antimikrobni učinak materijala za punjenje korijenskih kanala
   Type of Article:	original scientific paper
   MeSH:	ROOT CANAL FILLING MATERIALS + pharmacology ANTI-INFECTIVE AGENTS, LOCAL MICROBIAL SENSITIVITY TESTS
   Abstract:	The aim of this study was to evaluate the antimicrobial properties of three endodontic sealers (AH 26, Ketac-Endo and Apexit) using Direct Contact Test (DCT) and Agar Diffusion Test (ADT). DCT is based on measuring the effect of close contact between test bacteria and tested material, while ADT measures the areas of bacterial growth inhibition and consequently the incidence of microbial resistence of bacteria.The results of DCT showed that all tested materials, apart from Apexit, have antibacterial activity. The diameters of the bacterial growth inhibition zones in ADT demonstrated by Ketac-Endo (x=12.26 ± 1.76 mm), AH 26 (x=5.67 ± 0.66 mm) and Apexit (x=0.80 ± 0.29 mm).