List of Articles by Author
- Karlović Z, Jukić S, Miletić I, Britvić S, Osmak M, Anić I. The Mutagenic Potential of Chloroform, Orange Oil, Eucalyptus Oil and Halotane by Salmonella/Microsome Assay. Acta Stomatol Croat. 2004;38(1):39-45.
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| Title in English: |
The Mutagenic Potential of Chloroform, Orange Oil, Eucalyptus Oil and Halotane by Salmonella/Microsome Assay |
| Title in Croatian: |
Ispitivanje mutagenog potencijala kloroforma, narančinog ulja, eukaliptusovog ulja i halotana Salmonella /mikrosomskim testom. |
| Type of Article: |
original scientific paper |
| MeSH: |
CHLOROFORM
MUTAGENICITY TESTS |
| Abstract: |
The aim of this study was to examine mutagenic activity of four commercially available gutta-percha solvents by means of the Salmonella/ microsome assay. The examined solvents were: chloroform, orange oil, eucalyptus oil and halothane in amounts of 10 μl, 30 μl, 50 μl, 100 μl and 200 μl. Standard plate incorporation Ames test was preformed by using two tester strains of Salmonella typhimurium, TA 98 and TA 100, with metabolic activation of S9. The results showed toxicity of eucalyptus oil in all aliquots, orange oil in aliquots of 50 μl and above and chloroform in aliquots of 100 μl and 200 μl, but all four substances responded negative to the Ames test. These results indicate that the tested solvents do not possess mutagenic activity toward the Salmonella strains used. |
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