List of Articles by Author

NOTES:

*This author has been accepted with these names:

Brailo, Vlaho

*Articles are cited according to Uniform Requirements by International Committee of Medical Journal Editors - ICMJE and NLM Style Guide for Authors, Editors and Publishers

Picek P, Andabak Rogulj A, Vučićević-Boras V, Brailo V, Cigić L, Canjuga I, Ladika-Davidović B. Serum and Salivary Parameters in Patients with Recurrent Aphthous Ulcerations. Acta Stomatol Croat. 2012;46(1):43-9.

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Vučićević-Boras V, Rogić D, Brailo V, Vidović Juras D, Glažar I, Muhvić-Urek M. Sialochemistry in patients with oral lichen planus. Acta Stomatol Croat. 2011;45(3):184-9.

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Title in English:	Sialochemistry in patients with oral lichen planus
Title in Croatian:	Sijalokemijski nalaz za bolesnike s oralnim lihen planusom
Type of Article:	original scientific paper
MeSH:	(no MeSH data)
Abstract:	Objective: It is well known that certain salivary constituents might be disturbed in patients suffering from oral lichen planus (OLP), however, the results of the published studies are inconsistent. The aim of this study was to assess the concentrations of salivary analytes because most of them are part of salivary enzymes which maintain integrity of the oral mucosa which is compromised in OLP patients. Materials and Methods: In 25 patients with OLP (73±1.4 yrs) and in the 24 controls (24±3.7yrs) levels of total proteins, amylase, salivary magnesium, calcium, copper, chloride, phosphate, potassium and sodium were determined. Total proteins were determined by pyrogalol colorimetric method. Amylase levels were determined by continued colorimetric method. Salivary sodium, potassium and chloride were determined by indirect potentiometry whereas salivary copper and magnesium were determined by atomic absorption spectrophotometry whereas phosphates were determined by colorimetric method with use of molybdate. Statistical analysis was performed by use of χ2 test, Mann Whitney U test analysis of covariance and Spearman´s correlation. Results: Significantly higher concentration of salivary chloride was detected in OLP patients in comparison to the controls (p=0.025). Furthermore, when the obtained results for salivary analytes were adjusted with respect to the salivary flow rate, increased levels of salivary potassium, sodium, chloride and total proteins were found in patients with OLP when compared to the controls (p=0.622; p=0.504; p=0.600; p=0.586). Concentrations of salivary analytes were not affected by smoking habit. Conclusions: Increased levels of salivary sodium, potassium and chloride are probably a result of significant differences in salivary flow rate between patients with OLP and controls and do not indicate increased salivary antimicrobial activity.

Vučićević-Boras V, Canjuga I, Brailo V, Vidović Juras D. The effect of topical hyaluronic acid in patients with burning mouth syndrome. Acta Stomatol Croat. 2011;45(2):141.

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Title in English:	The effect of topical hyaluronic acid in patients with burning mouth syndrome
Title in Croatian:	Učinak lokalne primjene hijaluronske kiseline kod pacijenata sa sindromom pekućih usta
Type of Article:	letter to the editor
MeSH:	(no MeSH data)
Abstract:	Dear Editor, it has been reported that 0.2% hyaluronic acid (HA) might be beneficial in certain oral diseases such as recurrent aphthous ulcers and oral lichen planus due to its anti-inflammatory and other properties (1). Furthermore, HA is a hygroscopic macromolecule and solutions are highly osmotic. In the skin and perhaps on the oral mucosa, this property is likely to be relevant in controlling tissue hydration during periods of change such as the inflammatory process or response to tissue injury (2). Burning mouth syndrome is a still enigmatic condition for the patient and the doctor albeit extensive literature reports could be found. Unfortunately there is no effective treatment for BMS (3). In 19 patients with burning mouth syndrome a thorough clinical examination was performed as well as hematological investigation which involved complete blood count, iron, feritin and the BMS diagnosis was established according to the Scala et al.(4). HA was prescribed in the form of gel (Gengigel®, Ricerfarma, Italy) to be applied three times a day. After one year the participants were interviewed by the telephone. Out of 19 participants, we could reach only 12. In four patients complete BMS remission was reported after HA has been used for one month. In two patients the burning symptoms were reduced but were still present and in six patients burning symptoms were unaffected by use of HA, i.e. HA was not useful in BMS symptoms. It is possible that immediate application reduces discomfort and this is purely a barrier or protective mechanism from stimuli arising in the oral environment. On the other hand, complete remission of BMS might be solely attributed to the placebo effect which remains to be elucidated in further studies. However, we were satisfied as some patients were free of symptoms no matter what caused BMS remission.